| Sabotage? | Jack Chick | — | 1979 |
| Sabraman | Uri Fink | — | — |
| Sad Sack | George Baker | — | junio 1942 |
| Sadik | — | Italia | — |
| Safari callejero | Francisco Ibáñez | España | — |
| Safety Behind Bars | — | — | — |
| Saga de Xam | — | Francia | — |
| Saguaro (historieta) | — | Italia | — |
| Saint Sinner | Clive Barker | — | — |
| Sal y Pimienta | Sheldon Mayer | — | — |
| Samuel Sand | — | Italia | — |
| Sandman Midnight Theatre | — | Estados Unidos | — |
| Sandman: Obertura | Neil Gaiman | Estados Unidos | — |
| Sangre de barrio | Jaime Martín | España | 1989 |
| Savage Henry | Matt Howarth | — | — |
| Savage Tales | — | Estados Unidos | — |
| Savage Wolverine | Frank Cho | — | — |
| Savarese | — | Argentina | — |
| Saviour | Mark Millar | — | — |
| Savoir-fairy | Kurt Erichsen | — | 1986 |
| Scar face | Jack Chick | — | 1974 |
| Scarlet | Alex Maleev | — | — |
| Scarlet Traces | — | — | — |
| Scavengers | — | — | — |
| Scene of the Crime | Ed Brubaker | — | — |
| Sciuscià | — | Italia | — |
| Scout | Timothy Truman | — | — |
| Scud: The Disposable Assassin | Rob Schrab | — | — |
| Seaguy | Cameron Stewart | — | — |
| Secret doors | — | — | 1985 |
| Secret Love | — | — | — |
| Secret Santa | — | — | 17 de diciembre de 2014 |
| Secret service saucers | — | — | septiembre 1982 |
| Secret Weapon | — | Distrito de Hong Kong | — |
| Secrets Of The Ninja | Sean Michael Wilson | — | — |
| Secuestro aéreo | Francisco Ibáñez | España | — |
| See You In Memories | Pen So | — | — |
| Segis y Olivio, traperos de alivio | Jaume Rovira Freixa | — | — |
| Selective Yellow | — | — | — |
| Selector stirred WIXOSS | Mari Okada | Japón | 13 de febrero de 2017 |
| Senpai wa Dekapai | — | Japón | — |
| Sentient #1 | — | — | 12 de noviembre de 2019 |
| Sentient #2 | — | — | 12 de noviembre de 2019 |
| Sentient #3 | — | — | 12 de noviembre de 2019 |
| Sentient #4 | — | — | 12 de noviembre de 2019 |
| Sentient #5 | — | — | 12 de noviembre de 2019 |
| Sentient #6 | — | — | 12 de noviembre de 2019 |
| Seoul Jade | — | — | diciembre 1992 |
| Serenity: Downtime | — | — | 11 de noviembre de 2010 |
| Serenity: The Shepherd's Tale | — | — | 3 de noviembre de 2010 |
| Seule | Denis Lapière | — | 2018 |
| Sex-files of Chinese Swordsmen | Ren-Jie Mai | — | — |
| Shanghai Devil | — | Italia | — |
| Shaolin Cowboy | Geof Darrow | — | — |
| Sharaz-de: Tales from the Arabian Nights | Sergio Toppi | Italia | — |
| Shatter | — | Estados Unidos | — |
| Sheva's War | Christopher Moeller | — | — |
| Shi Fu | — | República Popular China | — |
| Shibaraku | Shin'ichi Fukuda | Japón | — |
| Shiny and Chrome | — | Estados Unidos | 25 de octubre de 2023 |
| Shogun Warriors | Doug Moench | — | — |
| Shot by a ray gun | Billy McKay | — | — |
| Shrugged | Michael Turner | — | — |
| Shukh. The Story of a Legend | — | Ucrania | — |
| Shutterbug Follies | Jason Little | Estados Unidos | — |
| Shūkan Shōnen Jump | — | Japón | — |
| Sienna | — | — | — |
| Siglo XX, ¡qué progreso! | Francisco Ibáñez | España | — |
| Sigurd | — | Alemania | — |
| Silas Finn | — | Italia | — |
| Silent War | David Hine | — | — |
| Silver Ocean | — | República Popular China | — |
| Silver Star | Jack Kirby | — | — |
| Simiocracia | Aleix Saló | España | 2012 |
| Simón "el escurridizo" | Bruguera Equip | España | 1986 |
| Sinawang | — | — | — |
| Siren Song | — | Estados Unidos | 27 de agosto de 2025 |
| Skarby Mirmiła | Janusz Christa | — | — |
| Sky Whale | — | Ucrania | — |
| Small World | — | — | 21 de diciembre de 2016 |
| Smilin' Jack coloring book | Zack T. Mosley | — | 1946 |
| Sniff's Holiday Camp | Lars Jansson | — | — |
| Sniff's Sport Shop | Lars Jansson | — | — |
| Snoopy's secret life | Charles M. Schulz | — | 1972 |
| Snorkmaiden Goes Rococo | Lars Jansson | — | — |
| Snotgirl | Bryan Lee O'Malley | Estados Unidos | 2016 |
| Snow House | — | — | — |
| Solar Wind | Paul Scott | — | — |
| Somebody goofed | Jack Chick | — | 1972 |
| Something to Fear | — | — | — |
| Son of mystery | Mark Millis | — | 1939 |
| Song of a Blackbird | Maria van Lieshout | — | 21 de enero de 2025 |
| SONGS of KAMUI | — | Japón | 6 de enero de 2024 |
| Sonic X | — | Estados Unidos | — |
| Sopa de pitufos | Peyo | — | 1976 |
| Space Battle Lunchtime 1 | Natalie Riess | — | — |
| Space Museum | Gardner Fox | — | — |
| Spaceman | Brian Azzarello | — | — |
| Spawn/Batman | Todd McFarlane | — | — |
| Spike vs. Dracula | Peter David | — | — |
| Spike: Asylum | Brian Lynch | Estados Unidos | — |
| Spitfire | — | Estados Unidos | — |
| Splinter Forever | — | Estados Unidos | — |
| Splinter's Wicked Headache | — | Estados Unidos | junio 1993 |
| Spy Superb #1 | — | — | 11 de enero de 2023 |
| Spy Superb #2 | — | — | 8 de febrero de 2023 |
| Spy Superb #3 | — | — | 15 de marzo de 2023 |
| Squeak the Mouse | Massimo Mattioli | Italia | — |
| Sq从你的名字开始 | — | República Popular China | — |
| Srebrny denar | Janusz Christa | — | — |
| Stacy: Attack of the Schoolgirl Zombies | — | Japón | 2001 |
| Stallion | Studio Kôsen | Estados Unidos | — |
| Star Crossed | Matt Howarth | — | — |
| Star Fox | — | — | — |
| Star Rangers | Mark Ellis | — | — |
| Star Spangled War Stories | — | Estados Unidos | — |
| Star Wars: Agent of the Empire | John Ostrander | — | — |
| Star Wars: Jedi Academy | Jeffrey Brown | — | — |
| Star Wars: Obsession | — | Estados Unidos | — |
| Star Wars: The Complete Classic Newspaper Comics | Archie Goodwin | — | 2018 |
| Star Wars: Vader Down | — | Estados Unidos | — |
| Stars and S.T.R.I.P.E. | — | — | — |
| Steampunk | Joe Kelly | — | — |
| Steget efter | — | Suecia | — |
| Step Aside, Pops | Kate Beaton | Canadá | 3 de septiembre de 2015 |
| Still the Ninja She Always Was | — | Estados Unidos | 28 de mayo de 2025 |
| Stonehaven | — | — | — |
| Storia d'Italia a fumetti di Enzo Biagi | — | Italia | — |
| Strange Bedfellows | Ariel Slamet Ries | Australia | 4 de marzo de 2025 |
| Strange Suspense Stories | Dennis O'Neil | — | — |
| Strange Weather Lately | Metaphrog | — | — |
| Strange Worlds | — | — | — |
| Strangehaven | Gary Spencer Millidge | — | — |
| Strangers | Rick Hoberg | — | — |
| Strangers in the Night | — | — | — |
| Strikeforce: Morituri | Brent Anderson | — | — |
| Stupid, Stupid Rat Tails | Thomas E. Sniegoski | — | 2000 |
| Sturmtruppen | Franco Bonvicini | Italia | — |
| Su vida privada | Francisco Ibáñez | España | — |
| Suburbia Highschool | David Füleki | — | — |
| Sueldecitos más bien bajitos | Francisco Ibáñez | España | — |
| Summer In Vale | — | República Popular China | — |
| Summer Shroud | Ilya Kuvshinov | — | — |
| Summer Temple Festival | — | — | — |
| Supa Strikas | — | Sudáfrica | — |
| Super Mario Bros. | — | Estados Unidos | — |
| Super Pig | Mário Freitas | — | — |
| Superboy and the Legion | — | Estados Unidos | — |
| Superboy and the Ravers | Karl Kesel | — | — |
| Supercrooks | Leinil Francis Yu | Estados Unidos | mayo 2012 |
| Superhero annual | — | — | — |
| Superman and Batman: World's Funnest | Evan Dorkin | — | — |
| Superman Confidential | B. Clay Moore | — | — |
| Superman vol. 2 | Brian Azzarello | Estados Unidos | — |
| Superman: Deadly Legacy | Jerry Siegel | — | — |
| Superman: Last Son of Earth | — | — | — |
| Superman: Speeding Bullets | Eduardo Barreto | — | — |
| Superman: The Feral Man of Steel | — | — | — |
| Superman: ¿Qué le pasó al hombre del mañana? | Alan Moore | Estados Unidos | — |
| Supermarket | Brian Wood | — | — |
| Supernatural Thrillers | Ron Goulart | — | — |
| Superworld Comics | — | — | — |
| Support your local Jew | Jack Chick | — | 1976 |
| Supreme : the return | Alan Moore | — | 2003 |
| Swapping Pads, part 1 | — | Estados Unidos | 30 de agosto de 2023 |
| Swapping Pads, part 2 | — | Estados Unidos | 27 de septiembre de 2023 |
| Swordsman Cat In Edo: The Twelve Lives Oiran | — | — | — |
| Sydney 2000 | Francisco Ibáñez | España | — |
| Syncopated Dreams | Mathilde Ramadier | — | — |
| Szranki i konkury | Janusz Christa | — | — |
| Šifra mistra Hanky | Tomáš Hibi Matějíček | — | 2007 |